Job Description

Company Overview

An innovative biotech startup focused on advancing the targeted delivery of biologics is seeking a skilled Molecular Engineering Scientist to join its growing team. Leveraging foundational academic science and a modular therapeutic platform, this organization is dedicated to improving the delivery and effectiveness of biologic therapies for challenging indications. The company fosters a collaborative and science-driven environment aimed at rapid discovery and development.

Position Summary

This role is ideal for a scientist or experienced associate passionate about bioconjugation, biologic purification, and analytical characterization. The successful candidate will support the production and analysis of a diverse pipeline of antibody-, peptide-, and oligonucleotide-based therapeutics. Responsibilities span early proof-of-concept studies to process optimization in a dynamic preclinical setting.

Key Responsibilities

• Conduct bioconjugation reactions, from initial feasibility to process refinement
• Purify biologics across various therapeutic formats and scales
• Develop and execute analytical methods to assess product quality and stability
• Maintain detailed laboratory records and communicate results effectively
• Manage and track materials, reagents, and samples used in studies
• Collaborate with cross-disciplinary teams including chemistry, biology, and CMC to support timely program advancement

Required Qualifications

• Advanced degree (MS or PhD) in Chemical Engineering, Bioengineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or related field
• 2-5 years of relevant experience in industry or academia
• Hands-on experience with bioconjugation techniques and purification workflows
• Proficiency in HPLC method development and troubleshooting
• Ability to prioritize multiple projects in a fast-paced environment

Preferred Qualifications

• Familiarity with a variety of conjugation strategies involving proteins, peptides, and oligonucleotides
• Background in protein engineering or organic synthesis
• Experience with Agilent OpenLab or similar data acquisition software
• Understanding of early-stage tech transfer and CMC readiness
• Exposure to biopharmaceutical characterization methods including MS, SPR, bioassays, and PK/PD evaluations
• Adaptability to startup environments with evolving systems and high ownership culture

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